Association of global brain damage and clinical functioning in neuropsychiatric systemic lupus erythematosus
نویسندگان
چکیده
منابع مشابه
Clinical implications of neuropsychiatric systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an auto immune disorder mediated by the immune complex and characterised by its protean clinical mani festation and multisystemic involvement (Mak 2007a). Neuropsychiatric manifestation of SLE (NPSLE) is one of the major and most damag ing presentations. It comprises a wide range of neurological syndromes affecting the central, peripheral and autonomic ne...
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Neuropsychiatric systemic lupus erythematosus (NPSLE) is the least understood, yet perhaps the most prevalent manifestation of lupus. The pathogenesis of NPSLE is multifactorial and involves various inflammatory cytokines, autoantibodies, and immune complexes resulting in vasculopathic, cytotoxic and autoantibody-mediated neuronal injury. The management of NPSLE is multimodal and has not been s...
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Background: Brucellosis is a zoonotic infection which is endemic in many countries. It is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon complication of brucellosis. Case presentation: A 25-year-old woman with a history of lupus for 5 months referred to the emergency ward of Shahid Beheshti Hosp...
متن کاملAbnormal brain diffusivity in patients with neuropsychiatric systemic lupus erythematosus.
BACKGROUND AND PURPOSE Neuroimaging techniques have increased our knowledge of the pathogenesis of neuropsychiatric systemic lupus erythematosus (NPSLE) and have been useful in supporting the diagnosis. Nevertheless, new imaging techniques are needed to unravel the exact pathogenesis and to provide diagnostic criteria for NPSLE. In this preliminary study, we investigated whether diffusion-weigh...
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Histiocytic necrotizing lymphadenitis or Kikuchi's disease is a rare, benign condition of unknown etiology, which is usually characterized by cervical lymphadenopathy and fever. This disease is rarely associated with systemic lupus erythematosus. Here we describe, for the first time in Iran, a patient who developed systemic lupus erythematosus about 3 years after the initial diagnosis of Kikuch...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 2002
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.10574